Institute of Innovative Research, 
Tokyo Institute of Technology.





  • 日時: 2019年11月13日(水)10:00~11:30
  • 場所: すずかけ台キャンパス  R2棟6階 大会議室
  • 講演題目 : Human iPSC-based Microphysiological Systems for Disease Modeling and Phenotypic Drug Screening
  • 講演者: Prof. Deok-Ho Kim, Ph.D(Department of Biomedical Engineering Johns Hopkins University School of Medicine)
  • 参加人数: 20名


My laboratory research focuses on the mechanobiology of human diseases and human organ/tissueon-a-chip platform technologies for regenerative biology, disease modeling, drug development, and precision medicine. In this talk, I will introduce human iPSC-derived microphysiological systems developed in our laboratory, including microphysiological models of inherited cardiomyopathy and peripheral neuropathy, bioengineered 3D human cardiac and skeletal muscle patches, and micro/nanofabricated platforms for drug efficacy/toxicity screening. Using these multi-scale biofabrication tools in combination with human pluripotent stem cell technologies, I will highlight how our biomimetic models helps to gain a better understanding of the structure-function relationship in complex 3D tissues, and serve as emerging platforms for disease biology studies and biotherapeutic development.