Institute of Innovative Research, 
Tokyo Institute of Technology.



The 17th International Biomedical Enginnering Seminar held(11/13)

  • Date: November 13, 2019
  • Venue: R2 bldg. 6F Large Meeting Room , Suzukakedai Campus
  • Title: Human iPSC-based Microphysiological Systems for Disease Modeling and Phenotypic Drug Screening
  • Speaker: Prof. Deok-Ho Kim, Ph.D(Department of Biomedical Engineering Johns Hopkins University School of Medicine)


My laboratory research focuses on the mechanobiology of human diseases and human organ/tissueon-a-chip platform technologies for regenerative biology, disease modeling, drug development, and precision medicine. In this talk, I will introduce human iPSC-derived microphysiological systems developed in our laboratory, including microphysiological models of inherited cardiomyopathy and peripheral neuropathy, bioengineered 3D human cardiac and skeletal muscle patches, and micro/nanofabricated platforms for drug efficacy/toxicity screening. Using these multi-scale biofabrication tools in combination with human pluripotent stem cell technologies, I will highlight how our biomimetic models helps to gain a better understanding of the structure-function relationship in complex 3D tissues, and serve as emerging platforms for disease biology studies and biotherapeutic development.