2019.11.14
The 17th International Biomedical Enginnering Seminar held(11/13)
- Date: November 13, 2019
- Venue: R2 bldg. 6F Large Meeting Room , Suzukakedai Campus
- Title: Human iPSC-based Microphysiological Systems for Disease Modeling and Phenotypic Drug Screening
- Speaker: Prof. Deok-Ho Kim, Ph.D（Department of Biomedical Engineering Johns Hopkins University School of Medicine）
Abstract:
My laboratory research focuses on the mechanobiology of human diseases and human organ/tissueon-a-chip platform technologies for regenerative biology, disease modeling, drug development, and precision medicine. In this talk, I will introduce human iPSC-derived microphysiological systems developed in our laboratory, including microphysiological models of inherited cardiomyopathy and peripheral neuropathy, bioengineered 3D human cardiac and skeletal muscle patches, and micro/nanofabricated platforms for drug efficacy/toxicity screening. Using these multi-scale biofabrication tools in combination with human pluripotent stem cell technologies, I will highlight how our biomimetic models helps to gain a better understanding of the structure-function relationship in complex 3D tissues, and serve as emerging platforms for disease biology studies and biotherapeutic development.
