Institute of Innovative Research, 
Tokyo Institute of Technology.


Press Release

Unveiling Novel Mechanism Underlying the Heat Shock Response in Escherichia coli

IbpA, a protein that partakes in the heat shock response in Escherichia coli bacteria, serves more functions than previously thought, as revealed by scientists at Tokyo Tech. Through in-depth experiments involving genetically engineered E. coli strains, the researchers find that IbpA suppresses the translation of messenger RNA of σ32, a master protein factor that regulates the expression of around a hundred genes of heat shock proteins, including IbpA itself.