Institute of Innovative Research, 
Tokyo Institute of Technology.


Press Release

Histone modifications are the influencers of zygotic genome awakening

Scientists at Tokyo Institute of Technology (Tokyo Tech) observed changes to the gene-regulating factors during zebrafish development and discovered that modifications to “histone H3”, one of the proteins around which DNA is bound, play an important role in “zygotic genome activation” or transition of control of zebrafish embryonic development from maternal material to the zygote.