Institute of Innovative Research, 
Tokyo Institute of Technology.


Press Release

Lamin C Facilitates Repair of Damaged Nuclear Envelope in Human and Mouse Cells

Using immunofluorescence and live-cell imaging, Tokyo Tech researchers were recently able to determine the mechanism underlying the repairing mechanism of the nuclear envelope, which play a key role in various physiologically relevant processes. The accidental rupture of the structure poses a hazard to the integrity of the mammalian nucleus. The study found that lamin C and related factors synergistically facilitate the repair process in mammalian cells.