Institute of Innovative Research, 
Tokyo Institute of Technology.


Press Release

Catching histones by the tail: a new probe to track histone modifications in living cells

Scientists at Tokyo Institute of Technology have developed a sensitive fluorescent antibody probe that specifically detects monomethylation of lysine 20 in histone H4 in living cells. This research has future implications and can be used to monitor the dynamics of histone modifications and genome integrity in single living cells without disturbing cellular functions.